The relationship between maternal serum apelin-36 level and anthropometric indices up to 18 months after birth; A cohort Study

Shiva Pourali Roudbaneh; Najmeh Tehranian; Ashraf Saber; Matin Sadat-Esmaeilzadeh; Anoshirvan Kazemnejad

doi:10.18233/APM43No4pp221-2292236

Shiva Pourali Roudbaneh
Najmeh Tehranian
Ashraf Saber
Matin Sadat-Esmaeilzadeh
Anoshirvan Kazemnejad

DOI: https://doi.org/10.18233/APM43No4pp221-2292236

Resumen

BACKGROUND & OBJECTIVE: Apelin plays an important role in regulating energy intake and homeostasis. This study aims to investigate the relationship between maternal serum apelin-36 and infants’ anthropometric markers up to 18 months after birth.

MATERIAL & METHODS: In this cohort study, 166 pregnant women aged 18-40 years old third trimester period referred to the Prenatal Clinic, participated in this study. The women were divided into two groups: an elective cesarean section group (as an exposure; n = 23), and a vaginal delivery group (as a non-exposure; n = 22). Maternal serum Apelin-36 levels were measured during the third trimester period and after delivery using ELISA. Infants were followed for up to 18 months during the postpartum period.

RESULTS: The serum level of Apelin-36 after delivery was significantly and positively correlated with the weight of infants at 12 months, and 18 months P<0.05. It was also correlated with the height of infants at 6 months P<0.05 and 18 months P<0.05. Additionally, Apelin-36 was significantly correlated with the head circumference at 12 months P < 0.05.

CONCLUSIONS: The maternal serum Apelin-36 level showed a relationship with the infant’s anthropometric indicators and gender.

Biografía del autor/a

Shiva Pourali Roudbaneh

MSc. in Midwifery Reproductive Health and Midwifery, Tarbiat Modares University, Tehran, Iran. PhD Scholar, Psychosocial health, and wellbeing research(emPoWeR) Unit. Department of Obstetrics and Gynecology, University of Melbourne, Victoria, Australia.

Najmeh Tehranian

Ph.D in Physiology, M.Sc of Midwifery, Associate Professor, Reproductive Health & Midwifery Department, Medical Sciences Faculty, Tarbiat Modares University, Tehran, Iran.

Ashraf Saber

M.Sc in midwifery, faculty member, Esfarayen Faculty of Medical Sciences, Esfarayen, Iran.

Matin Sadat-Esmaeilzadeh

MSc. in Midwifery, Department of Midwifery, Tarbiat Modares University, Tehran, Iran. Faculty member, Department of Midwifery, School of Nursing, Midwifery and Paramedicine, Guilan University of Medical Sciences, Rasht, Iran.

Anoshirvan Kazemnejad

Professor of Biostatistics, Department of Biostatistics, Tarbiat Modares University, Tehran, Iran.