Mitosis and its regulation

  • Alfredo de Jesús Rodríguez-Gómez Instituto Nacional de Pediatría
  • Sara Frías-Vázquez Instituto Nacional de Pediatría & Universidad Nacional Autónoma de México


Cell division by mitosis is essential for the development of organisms and
their reproduction; it is also necessary that each new cell is genetically
identical to that from which it comes. In eukaryotes this is achieved
by the presence of complex mechanisms that ensure the integrity of
genomic material and their proper segregation during mitosis. The traditional
view of mitosis has been divided into different stages that were
characterized by morphological studies in dividing cells; advances in
molecular biology have led beyond this characterization, so that we
now know a range of participant molecules. This article will discuss the
process of mitosis, both at the cellular and molecular level and a brief
summary of the molecular players that regulate this process.

Biografía del autor/a

Alfredo de Jesús Rodríguez-Gómez, Instituto Nacional de Pediatría
Laboratory of Cytogenetics, Department of Research
in Human Genetics
Sara Frías-Vázquez, Instituto Nacional de Pediatría & Universidad Nacional Autónoma de México
Department of Genomic Medicine and Envirionmental
Toxicology, Institute of Biomedical Research,


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Cómo citar
Rodríguez-Gómez, A., & Frías-Vázquez, S. (2014). Mitosis and its regulation. Acta Pediátrica De México, 35(1), 55-68.
Artículo de revisión