Simultaneous measurement of total transcutaneous bilirubin on forehead and chest as a predictive model for total serum bilirubin in premature and term newborns

  • María Esther Martínez Mercado Hospital de la Mujer de Aguascalientes, ISSEA.
  • Luis Fernando Torres Bernal Universidad Autónoma de Aguascalientes
  • Javier Góngora Ortega ISSEA
  • María del Rosario Sánchez Ortiz Hospital de la Mujer de Aguascalientes, ISSEA
  • José Antonio Guerrero Díaz de León Universidad Autónoma de Aguascalientes

Resumen

Background: detection of hyperbilirubinemia in neonates has become a challenge for healthcare systems. The objective of this study was to determine the usefulness of simultaneous measurements of total transcutaneous bilirubin on forehead (TTBf) and total transcutaneous bilirubin on chest (TTBs) as a predictive model for total serum bilirubin (TSB) in premature and term neonates.

Material and methods: a transverse and analytical study in neonates with gestational age between 30 and 42 weeks, from January 21 through April 30, 2013, at a public gynecology, obstetrics, and neonatology hospital. Pearson correlation was determined between TSB/TTBf and TSB/TTBs. Linear regression analyses were conducted for one and for several independent variables.

Results: for 89 simultaneous determinations the correlation between TSB/TTBf was 0.8411 and for TSB/TTBs 0.7942 (p < 2.2 E-16 for both cases). With the simple regression analysis between TSB and TTBf the equation was: TSB = 2.1187 + 0.7035 × TTBf (p < 2.2 E-16, R2 = 70.75%, R2 adjusted = 70.41%); for TSB and TTBs the equation was: TSB = 2.0405 + 0.6349 × TTBs (p < 2.2 E-16, R2 = 63.07%, R2 adjusted = 62.65%). With multiple regression analysis for TSB vs. TTBf, TTBs the equation was: TSB = 1.620 + 0.503 × TTBf + 0.224 × TTBs (p < 2.2 E-16, R2 = 72.87%, R2 adjusted = 72.24%).

Conclusions: it was proven that the model that included TTBf and TTBs allowed us to obtain a better prediction of TSB than models with a single measurement of TTB in hospitalized premature and term neonates.

Biografía del autor/a

María Esther Martínez Mercado, Hospital de la Mujer de Aguascalientes, ISSEA.
Attending Pediatrician of the Department of Neonatology
Luis Fernando Torres Bernal, Universidad Autónoma de Aguascalientes
Ophthalmologist. Doctor of Science, Department of
Surgery
Javier Góngora Ortega, ISSEA
Surgeon. Master of Science, Research Coordinator.
María del Rosario Sánchez Ortiz, Hospital de la Mujer de Aguascalientes, ISSEA
Pediatrician and Neonatologist. Department of
Neonatology.
José Antonio Guerrero Díaz de León, Universidad Autónoma de Aguascalientes
Doctor of Science, Department of Statistics.

Citas

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Publicado
2014-07-09
Cómo citar
Martínez Mercado, M., Torres Bernal, L., Góngora Ortega, J., Sánchez Ortiz, M., & Guerrero Díaz de León, J. (2014). Simultaneous measurement of total transcutaneous bilirubin on forehead and chest as a predictive model for total serum bilirubin in premature and term newborns. Acta Pediátrica De México, 35(2), 106-111. https://doi.org/10.18233/APM35No2pp106-111
Sección
Artículo original